Overview of implantable biomaterials: Definition, Timelines and progress. Different types of biomaterials (metals, ceramics, synthetic polymers, and biopolymers). Tissues structure and organization (vascular wall, cartilage, bone), Enzyme reactors based on nanostructured materials. Tissue engineering and regenerative medicine: Tissues structure and organization (vascular wall, cartilage, bone). Materials in Medicine; Biomineralization and Biomimetic Approaches; Thin films, grafts and coatings; Host Reaction to Biomaterials and Artificial Organs. Nanomaterials in bone substitutes and dentistry. Implants and Prosthesis. Reconstructive Intervention and Surgery. Nanorobotics in Surgery Engineering. Drug delivery. Therapeutic applications. Nanoscale biomaterials for medical and drug delivery devices. Gene technology and high throughput systems. Stem cell and precursor cell-based therapies