NANOSCALE BIOSYSTEMS (NTM 826)
An
introduction to the chemistry of amino acids, carbohydrates, lipids and nucleic
acids. Protein and enzyme structure and function. An introduction to cell
biochemistry. Self-assembly of peptides and proteins. Self-organizing systems. Synthesis,
assembling and encapsulation of nanoparticles. Isolation/ purification and
characterization of nanoparticles. Molecular modeling
and simulation.
Biointerfaces, nanoscale patterning, micro and nano-topography. Biomembranes, biomimetics, biochips,
bioseparation, biosensors, molecular recognition elements in nanosensing.
Biomicroelectromechanical systems (BioMEMS). Biomedical applications of nanomaterial devices. Nanomedicine: Diagnostics (colorimetric, fluorometric,
biosensors, surface Plasmon resonance), Disease diagnostics based on molecular
changes. Nanopharmacology. Therapeutics, Imaging. Physiological response to nanomaterials. Systematic and cellular
immunological responses to different nanomaterials.